TRBV28

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRBV28 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRBV28-associated genes across cancer lineages are FASN, NDRG1_pT346, and Chk2. Each is linked with TRBV28 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV28-to-partner and partner-to-TRBV28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV28→partner) and Y-score (partner→TRBV28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMFASN →-0.479-3.000.034.03531
SKCMNDRG1_pT346 →-0.612-2.584.044.01131
SKCMChk2 →-0.256-3.000.013.03431
SKCME-Cadherin →-0.895-3.169.027.01831
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration