TRBV26OR9-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TRBV26OR9-2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TRBV26OR9-2 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TRBV26OR9-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRBV26OR9-2 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

BLCA, THCA, and UCS are the cancer types where TRBV26OR9-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSTertileAll0.2220.383.00289view →
THCAOSTertileIV0.7500.972<.00163view →
UCSDFSMedianII,III,IV0.5500.171.00158view →
UVMDFSTertileAll0.2010.785.00154view →
KIRCOSMedianAll0.9060.843.00146view →
ACCOSMedianAll0.9160.719.00641view →
OVOSTertileIII,IV0.2180.329.01536view →
STADDFSTertileAll0.5840.802.00636view →
COADOSTertileIII,IV0.5370.826.00133view →
BRCADFSMedianIII,IV0.8570.755.01719view →
LIHCOSTertileAll0.1840.570.00615view →
PAADOSMedianAll0.4840.323.01713view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TRBV26OR9-2–BLCA (DFS)

Kaplan–Meier survival curve for TRBV26OR9-2 RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration