TRBV26

Across TCGA pan-cancer cohorts, TRBV26 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated TRBV26 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TRBV26 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRBV26 expression acts as an unfavorable survival marker, although some lineages such as LAML and ESCA show a favorable association.

UCEC, KIRC, and PAAD are the cancer types where TRBV26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.632	0.856	<.001	78	view →
KIRC	DFS	Tertile	IV	0.247	0.648	<.001	36	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	27	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
CESC	OS	Tertile	All	0.544	0.803	.016	24	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	21	view →
LUSC	OS	Tertile	II,III,IV	0.250	0.778	.007	18	view →
TGCT	OS	Tertile	All	0.814	0.968	.009	18	view →
LAML	DFS	Quartile	All	0.843	0.433	.002	18	view →
ESCA	OS	Tertile	III,IV	1.000	0.374	.043	12	view →
THYM	OS	Quartile	All	1.000	0.688	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

TRBV26–UCEC (DFS)

Open the UCEC breakdown →