TRBV24-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRBV24-1 mutation is significantly associated with the RNA expression of many other genes, with 127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRBV24-1-associated genes across cancer lineages are MIR548AZ, IGHVIII-22-2, and ZDHHC20P2. Each is linked with TRBV24-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV24-1-to-partner and partner-to-TRBV24-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV24-1→partner) and Y-score (partner→TRBV24-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMIR548AZ →+0.318+7.954<.001.00832
LUADIGHVIII-22-2 →+1.134+3.690<.001.00932
LUSCZDHHC20P2 →+0.065+4.496.005.00732
SKCMMIR1183 →+0.180+2.943<.001.00932
UCECRNA5SP361 →+0.232+4.069<.001.00832
UCECRNA5SP256 →+0.876+2.842<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

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