TRBV20-1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TRBV20-1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRBV20-1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher TRBV20-1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TRBV20-1 expression acts as an unfavorable survival marker.

SARC, GBM, and UCEC are the cancer types where TRBV20-1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCOSMedianAll0.0320.861<.00112view →
GBMDFSMedianAll0.0430.243.0036view →
UCECOSMedianIV0.2310.592.0366view →
PRADDFSMedianAll0.0990.886<.0016view →
LUSCOSMedianAll0.1760.724.0186view →
SKCMDFSMedianIII,IV0.0870.647.0133view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration