Across TCGA patient cohorts, TRBV2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TRBV2-associated genes across cancer lineages are CMP, Neutrophils, and pDC. Each is linked with TRBV2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRBV2-to-partner and partner-to-TRBV2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV2→partner) and Y-score (partner→TRBV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CMP →	+0.028	+2.314	<.001	.026	3	3
SKCM	Neutrophils →	+0.009	+1.439	.047	.044	3	1
UCEC	pDC →	+0.053	+3.180	.049	.010	3	1
UCEC	Erythrocytes →	+0.039	+3.071	.004	.017	2	1
LUAD	pro B-cells →	+0.147	+2.819	.003	.036	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TRBV2 survival (RNA) · tumor vs normal (RNA) · all TRBV2 data types