Across TCGA cell cohorts, TRBV19 protein abundance is significantly associated with the RNA expression of many other genes, with 515 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TRBV19-associated genes across cancer lineages are SEPTIN4, KCNAB3, and SEMA3E. Each is linked with TRBV19 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRBV19-to-partner and partner-to-TRBV19 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV19→partner) and Y-score (partner→TRBV19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SEPTIN4 →	+1.202	+1.622	.005	.002	3	2
BREAST	KCNAB3 →	+0.992	+2.106	.001	.001	3	2
BREAST	SEMA3E →	-2.785	-1.280	.004	.004	3	2
BREAST	AGAP5 →	+1.125	+1.510	.009	.008	2	3
BREAST	POLG2 →	+0.904	+1.252	.004	.005	3	2
LUNG_SCLC	POMT1 →	+0.953	+1.090	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 515 associations by consensus.

Exploration

TRBV19 survival (RNA) · tumor vs normal (RNA) · all TRBV19 data types