TRBV18

Across TCGA patient cohorts, TRBV18 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,319 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRBV18-associated proteins across cancer lineages are DOCK10, FYB1, and HCLS1. Each is linked with TRBV18 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRBV18-to-partner and partner-to-TRBV18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV18 versus DOCK10 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV18→partner) and Y-score (partner→TRBV18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK10 →	+0.472	+0.746	<.001	<.001	3	10
OV	FYB1 →	+0.742	+1.116	<.001	<.001	3	10
OV	HCLS1 →	+0.546	+0.843	<.001	<.001	3	10
UCEC	IL16 →	+0.697	+1.190	<.001	<.001	3	10
BRCA	SEPTIN1 →	+0.973	+1.089	<.001	<.001	3	10
BRCA	LCP2 →	+0.523	+0.994	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,319 associations by consensus.

TRBV18 vs DOCK10 — LSCC

Explore this scatter interactively →