TRBV16

Across TCGA patient cohorts, TRBV16 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,501 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV16-associated proteins across cancer lineages are SKAP1, GRAP2, and SEMA4A. Each is linked with TRBV16 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRBV16-to-partner and partner-to-TRBV16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV16 versus SKAP1 in CCRCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV16→partner) and Y-score (partner→TRBV16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SKAP1 →	+0.817	+0.702	<.001	<.001	3	6
CCRCC	GRAP2 →	+0.520	+0.489	<.001	<.001	3	6
UCEC	SEMA4A →	+0.629	+0.995	<.001	.007	3	5
OV	CD2 →	+1.044	+0.547	.006	.001	2	6
CCRCC	DOCK10 →	+0.362	+0.445	<.001	.001	3	5
LSCC	AIF1 →	+0.539	+0.548	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,501 associations by consensus.

TRBV16 vs SKAP1 — CCRCC

Explore this scatter interactively →