Across TCGA patient cohorts, TRBV12-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,019 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV12-2-associated proteins across cancer lineages are DOCK10, ZAP70, and ACAP1. Each is linked with TRBV12-2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRBV12-2-to-partner and partner-to-TRBV12-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV12-2→partner) and Y-score (partner→TRBV12-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK10 →	+0.371	+0.272	<.001	<.001	3	5
HNSC	ZAP70 →	+0.438	+0.363	.002	.006	3	4
LSCC	ACAP1 →	+0.418	+0.251	<.001	<.001	3	4
LSCC	FNBP1 →	+0.315	+0.214	<.001	<.001	3	4
BRCA	PTPRCAP →	+0.606	+0.142	.007	.008	3	4
OV	OTULINL →	+0.371	+0.359	.002	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,019 associations by consensus.

Exploration

TRBV12-2 survival (RNA) · tumor vs normal (RNA) · all TRBV12-2 data types