Across TCGA patient cohorts, TRBC2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRBC2-associated genes across cancer lineages are Tuberin_pT1462, Rictor, and Chk2_pT68. Each is linked with TRBC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBC2-to-partner and partner-to-TRBC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBC2→partner) and Y-score (partner→TRBC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin_pT1462 →	+0.345	+2.710	<.001	.003	3	2
LUAD	Rictor →	-0.544	-3.000	.023	.036	3	1
LUSC	Chk2_pT68 →	-0.139	-3.160	.019	.019	2	2
UCEC	A-Raf_pS299 →	-0.129	-2.459	.008	.019	3	1
UCEC	G6PD →	-0.280	-2.986	.036	.035	3	1
UCEC	GATA6 →	-0.182	-1.693	.005	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

TRBC2 survival (RNA) · tumor vs normal (RNA) · all TRBC2 data types