Across TCGA patient cohorts, TRAV8-3 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV8-3-associated genes across cancer lineages are RN7SL787P, RNA5SP534, and OR4K15. Each is linked with TRAV8-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV8-3-to-partner and partner-to-TRAV8-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV8-3→partner) and Y-score (partner→TRAV8-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL787P →	+0.071	+4.328	<.001	.007	3	2
UCEC	RNA5SP534 →	+0.604	+5.242	<.001	.007	3	1
SKCM	OR4K15 →	+0.025	+4.993	<.001	.002	3	1
SKCM	ANKRD36P1 →	+0.644	+3.449	<.001	.009	3	1
SKCM	OR51C1P →	+0.029	+4.328	<.001	.007	3	1
SKCM	RNU6-884P →	+0.510	+3.881	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

TRAV8-3 survival (RNA) · tumor vs normal (RNA) · all TRAV8-3 data types