Across TCGA patient cohorts, TRAV8-2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV8-2-associated genes across cancer lineages are Erythrocytes, Epithelial cells, and Th2 cells. Each is linked with TRAV8-2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAV8-2-to-partner and partner-to-TRAV8-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV8-2→partner) and Y-score (partner→TRAV8-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.039	+2.879	.006	.033	3	3
UCEC	Epithelial cells →	-0.096	-3.000	.020	.037	3	1
UCEC	Th2 cells →	+0.274	+2.815	.008	.036	2	1
UCEC	mv Endothelial cells →	-0.031	-2.989	.023	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TRAV8-2 survival (RNA) · tumor vs normal (RNA) · all TRAV8-2 data types