Across TCGA patient cohorts, TRAV8-1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV8-1-associated genes across cancer lineages are Bak, c-Kit, and Notch1. Each is linked with TRAV8-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV8-1-to-partner and partner-to-TRAV8-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV8-1→partner) and Y-score (partner→TRAV8-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bak →	+0.276	+3.321	.035	.010	3	1
UCEC	c-Kit →	-0.270	-3.321	.027	.010	2	1
UCEC	Notch1 →	+0.334	+3.321	<.001	.010	1	1
UCEC	Tuberin →	+0.316	+3.321	.025	.010	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TRAV8-1 survival (RNA) · tumor vs normal (RNA) · all TRAV8-1 data types