Across TCGA pan-cancer cohorts, TRAV7 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TRAV7’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where TRAV7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAV7 is over-expressed in tumor.
LUAD are the cancer types where TRAV7 tumor–normal differential expression is most reproducible.