Across TCGA patient cohorts, TRAV40 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV40-associated genes across cancer lineages are Skeletal muscle, NKT, and Endothelial cells. Each is linked with TRAV40 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV40-to-partner and partner-to-TRAV40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV40→partner) and Y-score (partner→TRAV40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Skeletal muscle →	+0.054	+3.010	.032	.020	3	1
UCEC	NKT →	-0.131	-3.000	.033	.037	2	1
UCEC	Endothelial cells →	-0.057	-2.957	.009	.037	1	1
UCEC	Erythrocytes →	+0.061	+3.000	<.001	.037	1	1
UCEC	lymphatic Endothelial cells →	-0.031	-2.946	.023	.037	1	1
UCEC	Mesangial cells →	-0.069	-2.989	.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

TRAV40 survival (RNA) · tumor vs normal (RNA) · all TRAV40 data types