Across TCGA patient cohorts, TRAV4 mutation is significantly associated with the RNA expression of many other genes, with 412 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV4-associated genes across cancer lineages are MIR4482, ATF4, and PYURF. Each is linked with TRAV4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV4-to-partner and partner-to-TRAV4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV4→partner) and Y-score (partner→TRAV4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4482 →	+1.045	+2.830	.002	.005	3	2
SKCM	ATF4 →	+0.646	+3.328	<.001	.005	3	2
SKCM	PYURF →	+0.649	+3.366	.003	.005	3	2
SKCM	SYNJ2BP-COX16 →	+0.453	+3.353	<.001	.005	3	2
UCEC	PIAS4 →	+0.506	+3.332	.001	.005	3	2
SKCM	NDUFB6 →	+0.596	+3.353	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 412 associations by consensus.

Exploration

TRAV4 survival (RNA) · tumor vs normal (RNA) · all TRAV4 data types