Across TCGA patient cohorts, TRAV4 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV4-associated genes across cancer lineages are CLP, Epithelial cells, and Endothelial cells. Each is linked with TRAV4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV4-to-partner and partner-to-TRAV4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV4→partner) and Y-score (partner→TRAV4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CLP →	+0.100	+3.019	.013	.019	3	1
UCEC	Epithelial cells →	-0.077	-3.321	.041	.010	3	1
SKCM	Endothelial cells →	-0.046	-3.315	.021	.010	2	1
SKCM	mv Endothelial cells →	-0.032	-3.315	.021	.010	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TRAV4 survival (RNA) · tumor vs normal (RNA) · all TRAV4 data types