TRAV36DV7

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAV36DV7 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV36DV7-associated genes across cancer lineages are Neurons, CD4+ memory T-cells, and Hepatocytes. Each is linked with TRAV36DV7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV36DV7-to-partner and partner-to-TRAV36DV7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV36DV7→partner) and Y-score (partner→TRAV36DV7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMNeurons →+0.028+2.854.003.03432
BLCACD4+ memory T-cells →+0.042+3.902<.001.01531
UCECHepatocytes →+0.012+3.162.029.01831
UCECMast cells →+0.021+3.212.017.01031
UCECPericytes →+0.030+2.113.037.02431
SKCMEndothelial cells →-0.043-2.315.027.03621
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration