Across TCGA patient cohorts, TRAV34 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV34-associated genes across cancer lineages are CICP13, RPL12P39, and RPL29P25. Each is linked with TRAV34 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV34-to-partner and partner-to-TRAV34 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV34→partner) and Y-score (partner→TRAV34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CICP13 →	+0.033	+3.208	<.001	.003	3	1
SKCM	RPL12P39 →	+0.071	+2.855	<.001	.009	3	1
SKCM	RPL29P25 →	+0.178	+3.557	<.001	.006	3	1
SKCM	RPL22P13 →	+0.204	+2.893	<.001	.006	3	1
SKCM	RPL34P23 →	+0.102	+3.010	<.001	.006	3	1
UCEC	MIR521-2 →	+0.507	+4.484	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

TRAV34 survival (RNA) · tumor vs normal (RNA) · all TRAV34 data types