TRAV30

Across TCGA pan-cancer cohorts, TRAV30 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TRAV30 data layer compared with 2 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TRAV30 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRAV30 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

SKCM, HNSC, and UVM are the cancer types where TRAV30 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.417	0.274	<.001	126	view →
HNSC	DFS	Median	IV	0.694	0.582	.003	74	view →
UVM	DFS	Tertile	II,III,IV	0.449	0.827	.001	63	view →
KIRC	DFS	Median	IV	0.635	0.247	.002	58	view →
COAD	DFS	Tertile	All	0.380	0.581	.002	45	view →
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	45	view →
KIRP	DFS	Tertile	IV	0.037	0.811	.006	35	view →
LAML	DFS	Median	All	0.510	0.253	.002	34	view →
STAD	OS	Tertile	IV	0.875	0.190	.005	21	view →
LUSC	DFS	Quartile	III,IV	0.561	0.192	.009	21	view →
THCA	DFS	Median	II,III,IV	0.882	0.502	.012	19	view →
ESCA	DFS	Median	All	0.487	0.918	.009	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TRAV30–SKCM (OS)

Open the SKCM breakdown →