Across TCGA pan-cancer cohorts, TRAV27 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TRAV27 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRAV27 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TRAV27 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD and SKCM are the cancer types where TRAV27 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.171	0.750	.002	6	view →
SKCM	DFS	Median	IV	1.000	0.201	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TRAV27 tumor-vs-normal RNA expression · all TRAV27 data types