Across TCGA patient cohorts, TRAV27 mutation is significantly associated with the RNA expression of many other genes, with 181 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV27-associated genes across cancer lineages are NUDT1, URGCP-MRPS24, and RNU6-370P. Each is linked with TRAV27 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV27-to-partner and partner-to-TRAV27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV27→partner) and Y-score (partner→TRAV27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUDT1 →	+0.838	+3.202	.001	.009	3	2
UCEC	URGCP-MRPS24 →	+0.383	+4.162	<.001	<.001	3	2
SKCM	RNU6-370P →	+0.205	+2.766	<.001	.006	3	2
UCEC	CDC45 →	+1.010	+3.223	.002	.009	3	2
SKCM	HIGD2A →	+0.479	+3.465	.008	.003	3	1
SKCM	LRCH4 →	+0.533	+3.198	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 181 associations by consensus.

Exploration

TRAV27 survival (RNA) · tumor vs normal (RNA) · all TRAV27 data types