Across TCGA patient cohorts, TRAV26-2 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible TRAV26-2-associated genes across cancer lineages are RPL17P19, CENPUP1, and C9orf62. Each is linked with TRAV26-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV26-2-to-partner and partner-to-TRAV26-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV26-2→partner) and Y-score (partner→TRAV26-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RPL17P19 →	+0.281	+5.548	<.001	.004	3	2
BLCA	CENPUP1 →	+0.181	+5.106	<.001	.008	3	1
BLCA	C9orf62 →	+0.049	+6.618	<.001	.001	3	1
BLCA	OR2W1 →	+0.046	+5.329	<.001	.006	3	1
BLCA	IGLJ7 →	+0.791	+5.177	<.001	.007	3	1
SKCM	PUDPP1 →	+0.058	+4.555	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

TRAV26-2 survival (RNA) · tumor vs normal (RNA) · all TRAV26-2 data types