Across TCGA patient cohorts, TRAV22 mutation is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV22-associated genes across cancer lineages are RRAS2P1, RN7SL107P, and RPL34P21. Each is linked with TRAV22 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV22-to-partner and partner-to-TRAV22 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV22→partner) and Y-score (partner→TRAV22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RRAS2P1 →	+0.875	+3.604	<.001	.001	3	1
SKCM	RN7SL107P →	+0.063	+3.034	<.001	.008	3	1
SKCM	RPL34P21 →	+0.143	+2.365	<.001	.007	3	1
SKCM	ARHGAP22-IT1 →	+0.107	+3.106	<.001	<.001	3	1
SKCM	CTSLP3 →	+0.101	+2.757	<.001	.001	3	1
LUAD	RNA5SP226 →	+0.465	+5.410	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

Exploration

TRAV22 survival (RNA) · tumor vs normal (RNA) · all TRAV22 data types