Across TCGA patient cohorts, TRAV22 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV22-associated genes across cancer lineages are Eosinophils, iDC, and Monocytes. Each is linked with TRAV22 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV22-to-partner and partner-to-TRAV22 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV22→partner) and Y-score (partner→TRAV22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Eosinophils →	+0.077	+2.538	<.001	.005	3	1
SKCM	iDC →	+0.192	+2.465	.012	.011	3	1
LUAD	Monocytes →	+0.026	+3.683	.035	.049	3	1
SKCM	Macrophages →	-0.034	-3.540	.019	.003	1	1
SKCM	Macrophages M1 →	-0.028	-3.527	.021	.003	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TRAV22 survival (RNA) · tumor vs normal (RNA) · all TRAV22 data types