Across TCGA pan-cancer cohorts, TRAV20 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TRAV20’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TRAV20 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRAV20 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

KIRC, THCA, and LUAD are the cancer types where TRAV20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRAV20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.753	<.001	10	view →
THCA	All	All	−0.473	<.001	3	view →
LUAD	Male	III,IV	+0.796	.025	1	view →
LUSC	All	All	−0.261	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: TRAV20 RNA expression & survival · all TRAV20 data types