Across TCGA patient cohorts, TRAV2 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV2-associated genes across cancer lineages are SETP5, SNORD62A, and OR7E53P. Each is linked with TRAV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV2-to-partner and partner-to-TRAV2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV2→partner) and Y-score (partner→TRAV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SETP5 →	+0.121	+2.866	.001	.008	3	1
SKCM	SNORD62A →	+0.585	+4.105	.001	<.001	3	1
SKCM	OR7E53P →	+0.044	+3.069	<.001	.009	3	1
SKCM	RN7SL837P →	+0.052	+3.993	<.001	.008	3	1
SKCM	RPS15P9 →	+0.326	+3.469	<.001	<.001	3	1
SKCM	MIR7845 →	+0.363	+2.864	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

TRAV2 survival (RNA) · tumor vs normal (RNA) · all TRAV2 data types