Across TCGA patient cohorts, TRAV19 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV19-associated genes across cancer lineages are Plasma cells, CD8+ Tem, and CLP. Each is linked with TRAV19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV19-to-partner and partner-to-TRAV19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV19→partner) and Y-score (partner→TRAV19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Plasma cells →	+0.025	+2.267	.007	.038	3	1
UCEC	CD8+ Tem →	+0.003	+4.481	<.001	.047	3	1
UCEC	CLP →	-0.060	-3.542	.048	.003	3	1
UCEC	Endothelial cells →	-0.045	-3.313	.015	.010	3	1
UCEC	lymphatic Endothelial cells →	-0.028	-3.531	.016	.003	3	1
UCEC	Macrophages M2 →	+0.010	+2.921	.036	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

TRAV19 survival (RNA) · tumor vs normal (RNA) · all TRAV19 data types