Across TCGA pan-cancer cohorts, TRAV16 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TRAV16 data layer compared with 23 for mass-spec protein.
The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TRAV16 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAV16 expression acts as an unfavorable survival marker.
BRCA are the cancer types where TRAV16 Mutation most reproducibly stratifies survival.