TRAV15

Across TCGA patient cohorts, TRAV15 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,058 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRAV15-associated GO terms across cancer lineages are Positive regulation of T cell proliferation, Antigen receptor-mediated signaling pathway, and Negative T cell selection. Each is linked with TRAV15 in more than 16 cancer types. Because this analysis shows association rather than direction, both TRAV15-to-partner and partner-to-TRAV15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T cell proliferation grouped by TRAV15-low versus TRAV15-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV15→partner) and Y-score (partner→TRAV15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of T cell proliferation →	+0.097	+0.078	<.001	<.001	3	17
STAD	Antigen receptor-mediated signaling pathway →	+0.097	+0.086	<.001	<.001	3	17
SKCM	Negative T cell selection →	+0.121	+0.061	<.001	<.001	3	17
STAD	Fc receptor signaling pathway →	+0.079	+0.073	<.001	<.001	3	16
STAD	Positive regulation of leukocyte cell-cell adhesion →	+0.101	+0.087	<.001	<.001	3	16
STAD	Positive regulation of CD4-positive, alpha-beta T cell activation →	+0.086	+0.088	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,058 associations by consensus.

Positive regulation of T cell proliferation by TRAV15 expression — STAD

Explore this box plot interactively →