Across TCGA patient cohorts, TRAV13-2 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV13-2-associated genes across cancer lineages are RPEP5, H3P2, and CDY7P. Each is linked with TRAV13-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV13-2-to-partner and partner-to-TRAV13-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV13-2→partner) and Y-score (partner→TRAV13-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPEP5 →	+0.055	+5.228	<.001	.001	3	1
SKCM	H3P2 →	+0.096	+2.705	<.001	.008	3	1
SKCM	CDY7P →	+0.012	+3.069	<.001	.009	3	1
SKCM	RN7SL831P →	+0.122	+4.219	<.001	.006	3	1
SKCM	SDHDP3 →	+0.143	+3.638	.009	.002	3	1
SKCM	MIR6882 →	+0.304	+3.458	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

TRAV13-2 survival (RNA) · tumor vs normal (RNA) · all TRAV13-2 data types