Across TCGA patient cohorts, TRAV13-1 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV13-1-associated genes across cancer lineages are RNA5SP54, RPL35P9, and USH2A-AS1. Each is linked with TRAV13-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAV13-1-to-partner and partner-to-TRAV13-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV13-1→partner) and Y-score (partner→TRAV13-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP54 →	+0.344	+4.260	<.001	.007	3	3
UCEC	RPL35P9 →	+0.413	+3.799	.002	.003	3	1
SKCM	USH2A-AS1 →	+0.102	+3.300	<.001	.001	3	1
SKCM	S100A11P1 →	+0.210	+3.597	.007	.006	3	1
SKCM	RN7SL837P →	+0.058	+4.186	<.001	.007	3	1
SKCM	BMPR1B-DT →	+0.312	+2.802	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

Exploration

TRAV13-1 survival (RNA) · tumor vs normal (RNA) · all TRAV13-1 data types