TRAV13-1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAV13-1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV13-1-associated genes across cancer lineages are Melanocytes, NK cells, and CD8+ naive T-cells. Each is linked with TRAV13-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV13-1-to-partner and partner-to-TRAV13-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV13-1→partner) and Y-score (partner→TRAV13-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMelanocytes →+0.093+3.031.007.01931
STADNK cells →+0.011+5.597<.001.04031
SKCMCD8+ naive T-cells →-0.038-2.980.027.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration