TRAV12-3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAV12-3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible TRAV12-3-associated genes across cancer lineages are Class-switched memory B-cells and Chondrocytes. Each is linked with TRAV12-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV12-3-to-partner and partner-to-TRAV12-3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV12-3→partner) and Y-score (partner→TRAV12-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMClass-switched memory B-cells →-0.040-2.712.031.03531
LUSCChondrocytes →+0.018+3.694<.001.02731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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