TRAV12-1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TRAV12-1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TRAV12-1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TRAV12-1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TRAV12-1 expression acts as an unfavorable survival marker.

KIRC are the cancer types where TRAV12-1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSMedianAll0.2630.810.01512view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration