TRAV12-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRAV12-1 mutation is significantly associated with the RNA expression of many other genes, with 206 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV12-1-associated genes across cancer lineages are RASSF1-AS1, ANKRD9, and MON1A. Each is linked with TRAV12-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV12-1-to-partner and partner-to-TRAV12-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV12-1→partner) and Y-score (partner→TRAV12-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRASSF1-AS1 →+0.416+3.341.002.00532
SKCMANKRD9 →+0.837+2.719<.001.00332
SKCMMON1A →+0.440+2.826.001.00132
SKCMPDXP →+0.704+2.851.001.00132
SKCMZFYVE19 →+0.383+3.220.004.00932
SKCMZNF771 →+0.423+3.360<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 206 associations by consensus.

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