TRAV11

Across TCGA patient cohorts, TRAV11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,680 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRAV11-associated GO terms across cancer lineages are CD8-positive, alpha-beta T cell activation, T cell receptor signaling pathway, and B cell homeostasis. Each is linked with TRAV11 in more than 16 cancer types. Because this analysis shows association rather than direction, both TRAV11-to-partner and partner-to-TRAV11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8-positive, alpha-beta T cell activation grouped by TRAV11-low versus TRAV11-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV11→partner) and Y-score (partner→TRAV11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD8-positive, alpha-beta T cell activation →	+0.090	+0.046	<.001	<.001	3	17
STAD	T cell receptor signaling pathway →	+0.088	+0.175	<.001	<.001	3	17
STAD	B cell homeostasis →	+0.107	+0.156	<.001	<.001	3	16
STAD	Alpha-beta T cell activation →	+0.081	+0.167	<.001	<.001	3	16
ESCA	Negative regulation of lymphocyte activation →	+0.075	+0.118	<.001	.003	3	16
STAD	Negative regulation of leukocyte cell-cell adhesion →	+0.071	+0.174	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,680 associations by consensus.

CD8-positive, alpha-beta T cell activation by TRAV11 expression — SKCM

Explore this box plot interactively →