Across TCGA patient cohorts, TRAV10 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV10-associated genes across cancer lineages are SMIM11P1, RNU4-70P, and TTTY2B. Each is linked with TRAV10 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAV10-to-partner and partner-to-TRAV10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV10→partner) and Y-score (partner→TRAV10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SMIM11P1 →	+0.275	+5.157	.002	.007	3	3
HNSC	RNU4-70P →	+0.643	+7.954	<.001	.008	3	1
HNSC	TTTY2B →	+0.009	+7.954	<.001	.008	3	1
LUAD	LINC00554 →	+0.028	+5.157	<.001	.007	3	1
UCEC	GUSBP7 →	+0.231	+2.814	.003	.003	3	1
UCEC	IL21 →	+0.204	+2.611	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

TRAV10 survival (RNA) · tumor vs normal (RNA) · all TRAV10 data types