TRAT1

Across TCGA patient cohorts, TRAT1 mutation is significantly associated with the RNA expression of many other genes, with 1,249 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAT1-associated genes across cancer lineages are RN7SL366P, ZWILCH, and AUNIP. Each is linked with TRAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAT1-to-partner and partner-to-TRAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL366P grouped by TRAT1-low versus TRAT1-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAT1→partner) and Y-score (partner→TRAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SL366P →	+0.180	+4.969	.002	.009	3	3
UCEC	ZWILCH →	+0.657	+3.601	<.001	.001	3	3
SKCM	AUNIP →	+0.468	+2.231	.004	.005	3	3
UCEC	RNFT2 →	+0.581	+2.332	.002	.003	3	3
UCEC	C18orf54 →	+0.669	+2.625	.001	.005	3	2
SKCM	CAVIN4 →	+0.705	+3.610	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,249 associations by consensus.

RN7SL366P by TRAT1 expression — GBM

Explore this box plot interactively →