TRAPPC9

Across TCGA cell cohorts, TRAPPC9 mutation is significantly associated with the RNA expression of many other genes, with 1,148 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRAPPC9-associated genes across cancer lineages are TREML4, IL17A, and LCE1B. Each is linked with TRAPPC9 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAPPC9-to-partner and partner-to-TRAPPC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TREML4 grouped by TRAPPC9-low versus TRAPPC9-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC9→partner) and Y-score (partner→TRAPPC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TREML4 →	+0.023	+3.044	.003	.008	3	2
BLOOD_Lymphoma	IL17A →	+0.195	+4.169	<.001	.002	3	2
BREAST	LCE1B →	+0.696	+4.554	<.001	<.001	3	2
LUNG_NSCLC_LUAD	RGR →	+0.015	+3.066	<.001	<.001	3	2
LUNG_NSCLC_LUAD	TMEM74 →	+0.620	+3.279	<.001	.005	3	2
LUNG_NSCLC_LUAD	ZNF721 →	+0.730	+3.206	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,148 associations by consensus.

TREML4 by TRAPPC9 expression — STOMACH

Explore this box plot interactively →