TRAPPC8

Across TCGA pan-cancer cohorts, TRAPPC8 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRAPPC8 data layer compared with 21 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TRAPPC8 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TRAPPC8 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where TRAPPC8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	IV	0.381	0.951	.006	15	view →
LUAD	OS	Tertile	II,III,IV	0.491	1.000	.026	7	view →
CCRCC	OS	Tertile	All	0.920	0.744	.028	6	view →
GBM	OS	Median	All	0.270	0.509	.028	2	view →
HNSC	DFS	Median	III,IV	0.715	0.889	.036	1	view →
LSCC	OS	Quartile	III,IV	0.441	0.905	.028	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TRAPPC8–PDAC (OS)

Open the PDAC breakdown →