TRAPPC8

Across TCGA cell cohorts, TRAPPC8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,634 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRAPPC8-associated GO terms across cancer lineages are Vesicle tethering, DNA synthesis involved in DNA replication, and Regulation of centrosome duplication. Each is linked with TRAPPC8 in more than 13 cancer types. Because this analysis shows association rather than direction, both TRAPPC8-to-partner and partner-to-TRAPPC8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering grouped by TRAPPC8-low versus TRAPPC8-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC8→partner) and Y-score (partner→TRAPPC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Vesicle tethering →	+0.104	+0.874	<.001	<.001	3	14
LUNG_SCLC	DNA synthesis involved in DNA replication →	+0.104	+0.876	.001	<.001	3	12
LUNG_SCLC	Regulation of centrosome duplication →	+0.144	+0.966	<.001	<.001	3	10
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.150	+0.946	<.001	<.001	3	10
STOMACH	Golgi organization →	+0.061	+0.864	.005	.002	2	11
LUNG_SCLC	Negative regulation of transcription by RNA polymerase I →	+0.104	+0.710	.002	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,634 associations by consensus.

Vesicle tethering by TRAPPC8 expression — URINARY_TRACT

Explore this box plot interactively →