TRAPPC6B

Across TCGA pan-cancer cohorts, TRAPPC6B mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TRAPPC6B data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TRAPPC6B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRAPPC6B expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

COAD, UCEC, and OV are the cancer types where TRAPPC6B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.911	1.000	.006	48	view →
UCEC	DFS	Tertile	All	0.947	0.739	.015	10	view →
OV	DFS	Tertile	All	0.676	1.000	.023	8	view →
LUAD	OS	Quartile	All	1.000	0.863	.009	8	view →
LSCC	DFS	Median	II,III,IV	0.974	0.874	.014	4	view →
PDAC	DFS	Quartile	III,IV	0.436	0.122	.017	2	view →
HNSC	DFS	Median	IV	0.900	0.700	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TRAPPC6B–COAD (DFS)

Open the COAD breakdown →