Across TCGA patient cohorts, TRAPPC4 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC4-associated genes across cancer lineages are FOXO3a_pS318_S321, Acetyl-a-Tubulin-Lys40, and IRS1. Each is linked with TRAPPC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC4-to-partner and partner-to-TRAPPC4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC4→partner) and Y-score (partner→TRAPPC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.169	-3.000	.019	.037	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.693	+3.000	.018	.037	3	1
UCEC	IRS1 →	+0.304	+3.000	.011	.037	3	1
UCEC	mTOR_pS2448 →	-0.264	-2.986	.002	.035	3	1
UCEC	PDCD4 →	-0.802	-3.000	.003	.037	3	1
UCEC	PKC-b-II_pS660 →	-0.319	-3.000	.046	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

TRAPPC4 survival (RNA) · tumor vs normal (RNA) · all TRAPPC4 data types