TRAPPC3

Across TCGA pan-cancer cohorts, TRAPPC3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TRAPPC3 data layer compared with 19 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TRAPPC3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TRAPPC3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, CCRCC, and GBM are the cancer types where TRAPPC3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	1.000	0.866	.010	16	view →
CCRCC	OS	Median	IV	0.123	0.785	.009	15	view →
GBM	DFS	Median	All	0.289	0.454	.002	7	view →
LSCC	DFS	Median	All	0.907	0.464	.009	6	view →
UCEC	OS	Median	III,IV	1.000	0.453	.012	4	view →
HNSC	DFS	Median	All	0.838	0.704	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TRAPPC3–LUAD (OS)

Open the LUAD breakdown →