TRAPPC3

Across TCGA patient cohorts, TRAPPC3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,345 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TRAPPC3-associated genes across cancer lineages are MICU3, TAMALIN, and SLC2A4. Each is linked with TRAPPC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRAPPC3-to-partner and partner-to-TRAPPC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRAPPC3 versus MICU3 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC3→partner) and Y-score (partner→TRAPPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MICU3 →	-0.737	-0.259	<.001	<.001	3	3
BRCA	TAMALIN →	-0.803	-0.226	<.001	<.001	3	3
BRCA	SLC2A4 →	-0.565	-0.193	.005	.005	3	3
HNSC	NR2F1-AS1 →	-0.760	-0.254	<.001	<.001	3	3
UCEC	PSTK →	-0.421	-0.159	.001	.002	3	3
LSCC	ADPRS →	+0.368	+0.168	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,345 associations by consensus.

TRAPPC3 vs MICU3 — BRCA

Explore this scatter interactively →