TRAPPC3

Across TCGA patient cohorts, TRAPPC3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC3-associated genes across cancer lineages are CD8+ naive T-cells, MEP, and Th1 cells. Each is linked with TRAPPC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC3-to-partner and partner-to-TRAPPC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by TRAPPC3-low versus TRAPPC3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC3→partner) and Y-score (partner→TRAPPC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.052	+3.202	<.001	.009	3	1
UCEC	MEP →	+0.033	+2.332	.017	.020	3	1
UCEC	Th1 cells →	+0.098	+2.321	.036	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ naive T-cells by TRAPPC3 expression — UCEC

Explore this box plot interactively →