TRAPPC2L

Across TCGA pan-cancer cohorts, TRAPPC2L mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TRAPPC2L data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TRAPPC2L mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TRAPPC2L expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and COAD are the cancer types where TRAPPC2L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.458	0.285	.004	25	view →
HNSC	DFS	Tertile	All	0.876	0.405	.020	13	view →
COAD	DFS	Tertile	II,III,IV	0.912	1.000	.038	6	view →
OV	DFS	Median	All	0.592	0.884	.017	4	view →
CCRCC	DFS	Median	III,IV	0.774	0.207	.047	4	view →
LUAD	DFS	Quartile	All	0.911	0.487	.009	2	view →
LSCC	DFS	Tertile	All	1.000	0.397	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TRAPPC2L–PDAC (OS)

Open the PDAC breakdown →