TRAPPC2B

Across TCGA patient cohorts, TRAPPC2B mutation is significantly associated with the RNA expression of many other genes, with 691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC2B-associated genes across cancer lineages are LINC01943, LINC00706, and HIRA. Each is linked with TRAPPC2B in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC2B-to-partner and partner-to-TRAPPC2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01943 grouped by TRAPPC2B-low versus TRAPPC2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC2B→partner) and Y-score (partner→TRAPPC2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01943 →	+0.688	+3.364	<.001	.004	3	1
UCEC	LINC00706 →	+0.107	+2.279	.003	.005	3	1
UCEC	HIRA →	+0.505	+3.721	.004	<.001	3	1
UCEC	CCDC134 →	+0.817	+2.606	<.001	.006	3	1
UCEC	DMC1 →	+0.745	+3.754	<.001	<.001	3	1
UCEC	PHF5A →	+0.639	+3.700	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 691 associations by consensus.

LINC01943 by TRAPPC2B expression — UCEC

Explore this box plot interactively →